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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e35eea372d22154f090017d80f02805b018721673eb82a2dd60183b884dc3d54' 
  AND token = '+CGdN/nbEb0fs7eeVjFMKN1Is0aYmLuxCFjeMypwjUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}