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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adf6a08b7db377998ea37f68e035a7cc8287999b04eb51bcc7db302f4aeebb1b' 
  AND token = 'E5W2xK/9sbE1TYm1m7zjgCaM7FzeyNCTzM+Tk7WdJoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}