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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ea6cb57031f66a6369ce10e407e634a0bf942c54e0afe640d95539cb533b71' 
  AND token = 'gnivulCN0ciH33fIZnTe8sLtlfXHCZIP1XGEcztEqms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}