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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550de970514f9b7f0fbdde8393b308b1d1a199cb819039d49c327694b152cf8a' 
  AND token = 'SuXs+R1STAePMhJJab3Z++dkvKA15HtO8+D0qw5Uy1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}