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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3841516d6b75fe0282f2d48357795aac92ccca91f645ea4c3fa58f5c168886' 
  AND token = 'FG70G4UacUAbJtRg0uBmnfCva4yMgEqc7g96igGMqoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}