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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '528d60e5a8e238751f22219cdb6226e22cc0e08dc570d43588c74439a3c5ce1d' 
  AND token = 'Qc6ENXtWz9oH1h+EBRGIWgBFDwDO1jQljLXLFl2et7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}