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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461ec6b6716efee2e02ad08b6198068c0eafc1d3de0693d5bcdc51ef5e11ee91' 
  AND token = 'k8dBykiv4j6HZFnh9IlIkjHCK3RKG1FQ6HMiqH9cCgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}