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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '366e81cd338094b40c12d4e026f72fd94f94cb8d816ee2dcb98c4165e79d69b9' 
  AND token = 'lvBhCHtxD3uU2UjfqmMK0tKfLjKfdu7nUgJ6x8OOOyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}