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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64dc73a9cf6df6c86401fc8326a2fc678aadb9e2d0a34b9aa6238c846f294c77' 
  AND token = '3/rg49TPyaznZiUsrzmHfB6tQ5/X4bQN3/hiitMvJuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}