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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b686853f44f1a8dfe74cf8cea006e2ead83e619977e712438fec1bfad062ac9' 
  AND token = 'MQ++CxtX38X+DH7/18i5MWDHnkEJwzAAI7JyvSS8jKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}