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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b9952d99ebef2a4ea16454d020dd17e3125ee6e81baef490dffede28496fc14' 
  AND token = 'DvwufbYYe1bqFP+5d9Tjy+ze8uaVR2R4nKz1Mz3dKE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}