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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef2510e8388ba3951361c936aacfc59af5dedf177e6d6ffe035dfdc211709af' 
  AND token = '+w3P9/yl8uzJLPG9F081j/k6KSz1uDnvm5Hx4KL0l0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}