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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '650275c29797f8ab005e7fd7cd3d8cf119ce7859e45313445347771813afd8a1' 
  AND token = 'mz7gd9pzCFLaPJPHE2+MQCeSEXv3vk8xX7c+8IJgTZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}