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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e54f88f4e7a526fe46dcd1c7f844d50bd447f89478c208c74b77766cd06978' 
  AND token = 'N8kSw8Q8vwPTuxbtYAYQ5+/VYN8b7Ou5tRTXAYaCods=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}