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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fb874629b43dfe33ac141a68d802220c4fd9d461e5739c3ca0740be9d07d00c' 
  AND token = '1BWvLrkMmWPdvFsO3Fk3MwrVZ9kYtvSEPHjbSXOmpNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}