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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ffe84deb0a94acbd2e6166fbfd6cdeae7e922a1e907fa442074df531cab21cd' 
  AND token = 'V33SGGDshUze61CqjmdY2d3W2fM9GZ0fqfFYkxnphdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}