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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41401c1b387b8235abf680799c4a9989758a7fcd890b8cb2cdb2fdf5fe34f50' 
  AND token = 'Tw+4c2qVvZ4Ts9q0fCLpu7YM0dNVOWwxj7UF6mLw4T4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}