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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd65cea2be0e98059f473679b13edee83f2cf1987d18c638e55fbcbadc7cbd3d9' 
  AND token = '+Rf7+7jOBZFgg5itYixPI7exr0xbObY4bLeDiwRAewc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}