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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '749fd7af6a5cc32bce709cba068228e722e1f816ffe09405fec2801113f58854' 
  AND token = 'KD9/47ahZjgkNnJTFvCutvtGvr2wXon8IT4HmEePfH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}