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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd88cb2239da96a4981601a66f2c78575495e6167aa45fa6ef78cee053447236b' 
  AND token = 'lMEO3oDWdZtMHqHRZ0w6AarSInm9MmSN+T33A0ssw7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}