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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc121c84faec1530b1cb9674aa7e686c89478a2fd3150978a094ba828b9e354d' 
  AND token = 'SzvTbHl/77LdwkqMFr328TCQM5RRXHkMUd+X2W04bKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}