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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a8df1da278eb79c5f50a4ac25651c5c4afcad8ad72ba78b685e554df4bb9dfc' 
  AND token = '/nN4gMODUzrL/Cc5fYzy97xOUsb4AsBqT53nJJxgDm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}