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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e415e848de6a0742d43a9cce23194e2daca1874f5095a84ea752515d450344d8' 
  AND token = 'ec8u8/8ILDgeRh4JP3fBgrHku1RJavV7fYjuNBGc7/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}