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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463cbcaa942f3747754ef7c89d4039ae8b5a51ca5187dc21515935c24a80d8f7' 
  AND token = 'OekVNyzYL8Iol9vrp8cE1a8vHGWSTpW3gQEJwgmywuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}