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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5273b1ba828f7ebe3c9a04d6b9607a7eedb45f031c6a753cfc6bb9afbd3fb86' 
  AND token = 'JaIPgEI7FbKYwfwfwct2lBUj45tf/j2FuQQeE06Lda0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}