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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f7b45eae7b05034e92831fb7f7a2ec2fdd529da601585fa9c329d5b6d47b64d' 
  AND token = 'Azb/yMvZWeeNZN17XG/pYs6JRJg7uG1mMvsN4471Wc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}