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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b37b86bf1b020a110a5c46a7d1607358fd6daa77468f36527219feaa17ae7cd' 
  AND token = 'YIUA+hIclo+dHQR4iTTKdm4USMJw1oVad9epZPpDYm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}