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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d522593d24d04f8a8f39e8ec160126d7f9144d045573103ce58523d5c5c2d3d' 
  AND token = 'wEyz0aEDunDNK/qj29HeVVuG/PemC9TmNiwXJqOzSy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}