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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c9e519e37bcd5a0503b050154cb4357a4b575b8b19c7c4ca6332dacbed9394a' 
  AND token = 'Mo9Vdea2MqEysX9l8xSqGS6Z/okuFy9l4odaxgW8phc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}