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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eab8607c292d0df8d090fe2f221124cdf941c33e3f8c7791deb2b41e6d5be1dd' 
  AND token = 'GdZZ0+DmyXlBhMmWjQEiyYVfTYdZ9oOevVQ1DfKVs9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}