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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce221e71aeb476f238c0c498c705ea4a8ed7992a0aaf53a2b6577107ac069fc0' 
  AND token = 'yObqpc5vPPL/9f3vyJtv1/N6x3UjGsFGhubyoMPvug4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}