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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e34d67213c1ab33b74fc50931b21b9ece0248e7746ae1983dc66f3ba504d17' 
  AND token = 'L5PbfKWii0t4eU5lW/S1KZ0qXBYzrghp9u6HO1dbFyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}