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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be98b827e4c1a4f0e9f7a9e873c8240d9d9f1a199d95e526f74d5024ac4cfdf' 
  AND token = 'IVL2KEnQAbVhVV02uMI+a8W02WvaQmYeyCi4mKrGDmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}