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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f982132285edc6d3789e891c12779b6dbc1b5ac51cc139aa5eb3a44ecc79e4b' 
  AND token = 'K6cJJqUEEVjOD5HqWgIs1N3xOHyAN/s0FvfYHfWYlaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}