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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '435c864209cf00e6d1b136e220dc1ebd7b4a1ff65b0c40d0898e544dd3d8c839' 
  AND token = 'Q8ByZTWS+HNEKx3glz95O0PSi23uxli/4rgMAsqxFD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}