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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849950349f73ca8dcc471d491ea9cd0f3ab495261c8772e21a4177453ee5e374' 
  AND token = 'HS0aznHoRBSyi8v1Mkfyt5j1X1239c5B17RxA0BYPDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}