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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54f7c57a2674be676fcbfac3b56f297794bd840dea83e62029197acdb9d3e590' 
  AND token = '5+VIetCk/rXU2ea0ro5Zp4HHVPTK+F6i1AKSzlqftPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}