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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3f0adda4092730d6c9767cb6d52d9266125ca9721cb8f6622bcffbaf74c07e' 
  AND token = 'DxFy9zS0Mu38h7+WXIZQyNPN8A0yvszfDCcTDhzdB30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}