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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae0d3ed56ce0d0c7b4903cbb4c35a80a20d739580729500b6a159035de62c96b' 
  AND token = 'VLdUAdmI9eopOFkK78lW/mOf20cmotOsTR8/Fr1aXdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}