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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a721a0a87571cbd02fc4b37b08407adfa3e344ccc381b36d0e95796747669c4' 
  AND token = '2fLSlPN5MYZFiHSvlLeB+Y+Nse2qjlrmQgp2pkjlRmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}