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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b508048dc22530265532556eddb5c0620d7f9f9f30ed318ec316efb072a5783' 
  AND token = 'BOK7Gte1sEzvIOzM+SB/P9wMkD3RrXOidW+1uaBhrPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}