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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7927fea69172c97a97ea9b06b7b9594b50f089abb923a1290c3d278f77c104' 
  AND token = '0PrbeLLa1+MxhyWLlb9u8o3mikmCyKNC/ETef3kkmKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}