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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e98d03655724901d6eb1a54941805d44c33a595098414d33395e4c7bb5b1a3b7' 
  AND token = 'I2qqzIVLTRCKf0CaduIduCJkMnt+KjURK163HUI7zUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}