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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbea30364ce98a20a958bb074d1889fdc48dfbc044071fec78a7fd7694799d6c' 
  AND token = '9kz9Q1IPoVhuQQz+A4ZpAALNPVinVJGUgR7G6Rjrmbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}