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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14278ccf8e631dd0f34c9ce1a67d1b2046e6248c852160915e43245fc0ba4745' 
  AND token = 'pvsv1we4kXU0ec6njd/Djq/3BDC7E6BBaFo605GtY1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}