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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb221967e5ca0c2636d43fd19bb08bc2e022965bcbc4c666d9543fe9cc50d93d' 
  AND token = 'KU3hAqdJRRL6gkF9m+tbt7iMauhW7WO+A1W9mOrje2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}