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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff593340912c19124f82dd86fbeedcc824e8bc61d6704f03be4b63ecc1460bf6' 
  AND token = '6m/ZMbVNaN/R9r1utGr3K9MRYn6BCf4cMQc7KPVpR8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}