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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01f061aa2bc7a47eac6d4fdeb91d376e01035e594e751d47f83928e03c4c2ac2' 
  AND token = 'CdAouM9shG5+Rz5Hj5YkqRfVqcu0t0TM3FkNOuYY6OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}