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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa3849850c9c104294048bb5a5ad4d1ef739d5708a8b78048ca69df0061e38db' 
  AND token = '+iYeLwYO6W0bnDCMowufgoGbO6oOKsOe/Fc5DK8+rkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}