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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cb7cd33ac581f8bc113cf6f5afb09432910ba333272d7a014551a28f7182878' 
  AND token = 'UeDIjJ7kk2vIWF0y8EqCjHpaliGxvMA3lAXrWru3AtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}